Geographical Variation and Risk of Breast Cancer in Relation to ABO Blood Group System

Authors

  • Satyam Prakash Assistant Professor, Department of Biochemistry, Janaki Medical College Teaching Hospital, Tribhuvan University, Janakpurdham
  • Nand Kishore Sah Associate Professor, Department of Community Medicine, Janaki Medical College Teaching Hospital, Tribhuvan University, Janakpurdham
  • Khushbu Yadav Lecturer, Department of Microbiology, Krishna Medical Technical Research Center, Purwanchal University, Janakpurdham
  • Jitendra Kumar Singh Assistant Professor, Department of Community Medicine, Janaki Medical College Teaching Hospital, Tribhuvan University, Janakpurdham

DOI:

https://doi.org/10.7439/ijbr.v7i7.3465

Abstract

Background and Objectives: Breast cancer is the second most common malignancy which is a life threatening disease among young premenopausal women affecting their sexuality, femininity, body image, and maternal issues following mastectomy may lead the women to face psychiatric co-morbidity. Methods: The data was collected from hospital records, patients documents and annual reports which were verified with respective authorities. Collected data was analyzed by using SPSS 17.0 and was considered statistically significant at p-value ? 0.05. The adjusted Odds Ratios (OR) and 95% confidence Interval (CI) was also estimated. Results: The risk of developing breast cancer differed significantly by ABO blood type in each of the two cohorts (p = 0.97) and this association between blood group and breast cancer risk was highly similar between the two independent populations. The adjusted risks of breast cancer associated with blood groups A, B, and AB were insignificant with risk factors for the disease. The association between ABO blood group and the subsequent risk of breast cancer was not modified to a statistically significant extent by age, BMI, age at menarche, menopausal status, marital status and smoking status. Conclusion: The association between blood group and breast cancer risk was insignificant and is still controversial. Further studies are necessary to identify the mechanisms by which ABO blood type may influence the risk of breast cancer.

Downloads

Download data is not yet available.

Downloads

Published

2016-07-30

Issue

Vol. 7 No. 7 (2016): Jul

Section

Original Research Articles

License

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
  • An author must submit Copyright form After acceptance of the article.

How to Cite

1.
Geographical Variation and Risk of Breast Cancer in Relation to ABO Blood Group System. Int Jour of Biomed Res [Internet]. 2016 Jul. 30 [cited 2026 Mar. 19];7(7):482-9. Available from: https://www.ssjournals.co.in/index.php/ijbr/article/view/3465