Perioperative anesthesia management in patients with sickle cell hemoglobinopathies for open heart surgery: Retrospective analysis of 15 cases

Abstract

Introduction: Sickle cell hemoglobinopathies spectrum varies from benign sickle cell trait to fatal sickle cell disease. It is recessively inherited genetic disorder, results from mutation chromosome 11 which further ends up matching with valine rather than glutamine at globin gene. Occurance is common in india specifically in central india. Hypoxia, hypercarbia, hypothermia, dehydration increases sickling and these events are not uncommon in intra and postoperative periods in patients undergoing cardiac surgery on cardiopulmonary bypass. Timely and proper interventions by anesthesiologist are needed to avoid these events and improve outcome of patients. Methodology: We here analyzed successful outcome of 15 cases done in 2 years at Achary Vinoba Bhave Rural Hospital Sawangi meghe, Wardha and discussed in details interventions for better outcome of patients undergoing cardiac surgery on cardiopulmonary bypass. Conclusion: By following multidisciplinary approach, intra and post operative course was uneventful and with sickle levels such as those presented here, we feel that this technique has significant benefits.