Effects of Oral Diazepam on Visual Functions of Healthy Nigerian Volunteers

Authors

  • Igwe S. A. Department of Pharmacology and Therapeutics, College of Medicine, Enugu State University of Science and Technology, Enugu
  • Nwobodo N. N. Department of Pharmacology and Therapeutics, Ebonyi State University, Abakaliki,
  • Ibezim O. I. Department of Optometry,Abia State University, Uturu
  • Igwe J. I. Department of Public Health, Enugu State University of Science and Technology, Enugu

DOI:

https://doi.org/10.7439/ijbr.v6i6.2092

Keywords:

Atonic Postpartum haemorrhage, Intraperitoneal bleeding following caesarean section, Complications of caesarean section, Uteine massage, Rectus sheath hematoma, Inferior epigastric vessels

Abstract

Objectives : Diazepam, a benzodiazepine is used clinically for its anxiolytic, sedative-hypnotic, muscle-relaxant effects, and when used therapeutically, little or no attention is paid to its ocular effects or manifestations. Methods : The ocular manifestations or signs after therapeutic ingestion of diazepam on visual functions were determined in ten healthy young adult volunteers. The following visual functions were assessed: pupil size, amplitude of accommodation, near point of convergence, visual acuity at near and far, as well as distant and near phoria. Results : Revealed that diazepam has no effect on the pupil diameter, as well as near and distant visual acuity, while the near point of convergence and the amplitude of accommodation increased by 51% and 13.4% respectively. However, the phoria status tended towards orthophoria thereby enhancing existing heterophoria. Conclusion : Consequently, there is need for close monitoring to avoid negative effects on vision following prolonged use of diazepam.

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Published

2015-06-30

Issue

Vol. 6 No. 6 (2015): Jun

Section

Original Research Articles

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How to Cite

1.
Effects of Oral Diazepam on Visual Functions of Healthy Nigerian Volunteers. Int Jour of Biomed Res [Internet]. 2015 Jun. 30 [cited 2026 Mar. 17];6(6):421-4. Available from: https://www.ssjournals.co.in/index.php/ijbr/article/view/2092