The Recessive model of 677C>T Polymorphism in MTHFR gene increase moderately the risk of Colorectal Cancer in Moroccan patients

Authors

  • Falak Azzam Biochemistry and immunology laboratory, Mohammed V University, Faculty of Sciences Rabat
  • Abdelilah Laraqui Mohammed V Military Hospital, Biosecurity P3 Laboratory
  • Fatima El Boukhrissi Moulay Ismail Military Hospital, Biochemistry Laboratory
  • Hicham El Rhaffouli Mohammed V Military Hospital, Biosecurity P3 Laboratory
  • Youssef Bakri Biochemistry and immunology laboratory, Mohammed V University, Faculty of Sciences Rabat
  • Rachid Aboukhalid Biochemistry and immunology laboratory, Mohammed V University, Faculty of Sciences Rabat
  • Idriss Lahlou-amine Mohammed V Military Hospital, Biosecurity P3 Laboratory
  • Saad Amzazi Biochemistry and immunology laboratory, Mohammed V University, Faculty of Sciences Rabat

DOI:

https://doi.org/10.7439/ijbr.v6i6.2054

Keywords:

HIV, Bone marrow, Anaemia

Abstract

Methylenetetrahydrofolate reductase (MTHFR) is a critical folate-metabolising enzyme and a polymorphism at position 677 (C677T), is associated with reduced enzyme activity. We investigated whether this functional polymorphism modulates the risk of developing Colorectal Cancer (CRC).

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Published

2015-06-30

Issue

Vol. 6 No. 6 (2015): Jun

Section

Original Research Articles

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How to Cite

1.
The Recessive model of 677C>T Polymorphism in MTHFR gene increase moderately the risk of Colorectal Cancer in Moroccan patients. Int Jour of Biomed Res [Internet]. 2015 Jun. 30 [cited 2026 Mar. 19];6(6):374-8. Available from: https://www.ssjournals.co.in/index.php/ijbr/article/view/2054