International Journal of Advances in Scientific Research
type: channel
description: International Journal of Advances in Scientific Research (IJASR) is monthly online peer-reviewed open access multidisciplinary journal dedicated to publishes articles from the broad field of basic science and scientific research. ISSN: 2395-3616 (Online)
publisher: Scholar Science Journals
language: en
publication name: International Journal of Advances in Scientific Research
issn: 2395-3616
copyright: Authors who publish with this journal agree to the following terms: Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).
items: Immediate release tablet formulations: Formulation strategies, superdisintegrants, and evaluation parameters with special reference to antihypertensive drugs
items: Mucoadhesive microspheres: A review
items: Buccal films as an emerging drug delivery platform
items: A review on Ethogel for topical application
items: Chemotherapeutic induced neuropathic pain. A review from the literature focusing on its treatments
items: RP-HPLC force degradation profile of antidiabetic drugs
items: Estimation of ibuprofen and famotidine by (RP-HPLC)
items: Management of vataj type of Shirshula with Goghrit Pratimarsha nasya- A case report
items: HFMD- A Fuzzy Game Theory Model
items: Systematizing Astrology for Constructive Approach
items: Artificial Intelligence in Orthodontics: Prediction and Planning
items: Association between plasma homocysteine levels and coronary artery disease.
items: Genotoxicity effects of selected alcoholic polyherbal products using Allium cepa
items: The Impact of Culture on Scientific Development
items: Astrology: A Scientific Purview
items: Challenges of pandemic disease and mental health concern in Ethiopia: A systematic review of literature
items: Literature Review on the Bamboo as a Sustainable Material for Interiors with Its Potential and Market Assessment
items: Is pre vaccination the reason for less morbidity and mortality for COVID-19 in India: an epidemiological study
items: Histopathologic review of ovarian teratoma in Port Harcourt: A multicenter study
items: Artificial neural networks for medical diagnosis: A review of recent trends
items: Can technology save the environment?
items: Anti-ulcer potential of the Ethanolic Extract of leavesof Solanum Violaceum in Wistar albino rats
items: Hepatitis C - Challenges and New Approaches in Vaccine Development
items: Sensitivity of various methods (CMT, CE and Indicator Paper) of subclinical cattle mastitis diagnostic in some dairy cows breeding in east of Algeria
items: Altitudinal Variation in Alkaloid Composition of Hyoscyamus niger: A study with reference to Kashmir region of Himalayas
items: Comparative studies of NiMnCo3O4 thin film electrodes for super capacitors applications
items: An updated review on pharmaceutical mini tablets: Formulation and it
items: Differentiated Ontologies
items: Peptide Conjugated Lipid Nanoparticles and Cancer Drug Delivery
items: Study of the effect of intercropping on the physicochemical characteristics of castor bean, soybean, cowpea and common bean seeds after cultured in two agroecological zones of Cameroon

Immediate release tablet formulations: Formulation strategies, superdisintegrants, and evaluation parameters with special reference to antihypertensive drugs
type: item
description: Immediate-release (IR) tablets represent the most widely utilized solid oral dosage forms owing to their simplicity, cost-effectiveness, and ability to provide rapid therapeutic action. In the management of cardiovascular disorders such as hypertension, prompt drug availability is often essential to achieve effective clinical outcomes. Antihypertensive agents, particularly β-adrenergic blockers, are commonly formulated as immediate-release dosage forms to ensure quick onset of action. Esmolol hydrochloride, a cardioselective β₁-blocker with rapid onset and short duration of action, serves as an ideal model drug for studying immediate-release formulation strategies. This review discusses the principles of immediate-release tablet formulation, selection of excipients with emphasis on superdisintegrants, manufacturing techniques, and evaluation parameters. The role of formulation variables in influencing disintegration and dissolution behavior is highlighted, along with recent advances in immediate-release tablet technology. The review aims to provide a comprehensive overview of formulation approaches for immediate-release tablets of antihypertensive drugs, supporting the development of effective and reliable oral dosage forms.
subject: Review Articles
  topic: section
subject: Immediate release tablets
  topic: keywords
subject: antihypertensive drugs
  topic: keywords
subject: superdisintegrants
  topic: keywords
subject: direct compression
  topic: keywords
subject: Pharmacy
  topic: subjects
subject: Pharmaceutics
  topic: disciplines
creator: Indrasen Chand Maurya
creator: Shweta Shukla
creator: Om Prakash Agrawal
rights: Copyright (c) 2025 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2025-12-19
publication date: 2025-12-19
starting page: e5889
ending page: e5889

Mucoadhesive microspheres: A review
type: item
description: Mucoadhesive microspheres are an advanced multiparticulate drug delivery system designed to enhance drug residence time at mucosal surfaces and provide controlled or sustained drug release. By combining the advantages of mucoadhesion and microsphere technology, these systems improve bioavailability, reduce dosing frequency, and enhance patient compliance, particularly for drugs with short half-lives or limited absorption windows. This review discusses the fundamentals of mucoadhesive microspheres, mechanisms of mucoadhesion, polymers used, methods of preparation, evaluation parameters, drug release behavior, applications, challenges, and future perspectives.
subject: Review Articles
  topic: section
subject: Mucoadhesive microspheres
  topic: keywords
subject: Controlled drug delivery
  topic: keywords
subject: Chitosan
  topic: keywords
subject: Bioadhesion
  topic: keywords
subject: Multiparticulate systems
  topic: keywords
subject: Pharmaceutics
  topic: subjects
subject: Pharmaceutics
  topic: disciplines
creator: Sanjay Kumar
creator: Shweta Shukla
creator: Om Prakash Agrawal
rights: Copyright (c) 2025 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2025-12-19
publication date: 2025-12-19
starting page: e5887
ending page: e5887

Buccal films as an emerging drug delivery platform
type: item
description: Buccal films have emerged as a promising drug delivery platform due to their ability to bypass hepatic first-pass metabolism, improve bioavailability, enhance patient compliance, and provide controlled or rapid drug release. These thin, flexible polymeric films adhere to the buccal mucosa and allow systemic or local delivery of a wide range of therapeutic agents. This review discusses the anatomy and physiology of the buccal mucosa, advantages and challenges of buccal film systems, polymers used for film development, formulation techniques, evaluation parameters, recent advancements, and applications in modern drug delivery. The review concludes that buccal films offer an efficient, patient-friendly, and technologically adaptable platform that will continue to expand in pharmaceutical applications.
subject: Review Articles
  topic: section
subject: Buccal films
  topic: keywords
subject: Mucoadhesion
  topic: keywords
subject: Polymeric films
  topic: keywords
subject: Transmucosal delivery
  topic: keywords
subject: Drug delivery systems
  topic: keywords
subject: Pharmacy
  topic: subjects
subject: Pharmaceutics
  topic: disciplines
creator: Ashutosh Dinkar Nerkar
creator: Ayush Pratap Singh Sengar
creator: Raghuraj Lovanshi
creator: Om Prakash Agrawal
rights: Copyright (c) 2025 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2025-11-30
publication date: 2025-11-30
starting page: e5883
ending page: e5883

A review on Ethogel for topical application
type: item
description: Topical drug delivery remains a challenging field due to the barrier nature of the skin (especially the stratum corneum). Vesicular systems such as ethosomes have emerged as promising nanocarriers for improved dermal/ transdermal delivery. When such ethosomal suspensions are incorporated into gel bases, the resultant formulations are termed “ethogel” (or nano‐ethogel) and offer advantages of enhanced skin permeation, deposition, sustained release and better patient compliance. This review critically examines the formulation science of ethogel, its mechanisms of action, evaluation parameters, applications (especially in dermatology and oncology), formulation challenges, regulatory and translational aspects, and future prospects.
subject: Review Articles
  topic: section
subject: Ethogel
  topic: keywords
subject: Vescular System
  topic: keywords
subject: Nano-Gel
  topic: keywords
subject: Topical Drug Delivery System
  topic: keywords
subject: Ethogel
  topic: subjects
subject: Pharmaceutics
  topic: disciplines
creator: Om Prakash Agrawal
creator: Dhiraj Kumar Gupta
creator: Sailesh Kumar Ghatuary
rights: Copyright (c) 2025 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2025-11-01
publication date: 2025-11-01
starting page: e5879
ending page: e5879

Chemotherapeutic induced neuropathic pain. A review from the literature focusing on its treatments
type: item
description: Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating adverse effect of many anticancer agents, presenting with sensory symptoms such as spontaneous pain and mechanical or cold allodynia in a characteristic "stocking and glove" distribution. This neuropathic pain can severely limit the dosage and duration of life-saving chemotherapy, often necessitating treatment modification or cessation, and may persist long after therapy, impairing survivors’ quality of life. Standard pharmacological treatments offer limited efficacy, highlighting the need for alternative therapies. This review summarizes current literature on emerging treatments for CIPN, with a focus on three agents: nabiximols, gabapentin, and phenyl N-tert-butylnitrone (PBN). Nabiximols, a cannabinoid-based oral spray, demonstrated modest efficacy and a favorable safety profile in a small pilot study, suggesting the need for larger clinical trials. Gabapentin, an anticonvulsant, showed potential as an early intervention in patients with mild symptoms, with good tolerability and safety. PBN, a potent free radical scavenger, prevented the development of neuropathic pain in preclinical models of paclitaxel-induced neuropathy, offering promising neuroprotective effects. Collectively, these findings underscore the importance of further clinical and translational research to identify and validate effective therapies for managing CIPN.
subject: Review Articles
  topic: section
subject: CIPN
  topic: keywords
subject: Gabapentin
  topic: keywords
subject: Neuropathic
  topic: keywords
subject: Anticonvulsant
  topic: keywords
subject: Pharmacology
  topic: subjects
subject: Pharmacy
  topic: disciplines
creator: Partha Sarathi Datta
creator: Joydeb Acharjee
rights: Copyright (c) 2017 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2018-01-09
publication date: 2018-01-09
starting page: 138
ending page: 140
doi: 10.7439/ijasr.v3i12.5808

RP-HPLC force degradation profile of antidiabetic drugs
type: item
description: A force degradation profile was developed of Metformin (MET) & Pioglitazone (PIOG) in pharmaceutical combine tablet dosage form on RP-HPLCusing Comosil RP-C18 (4.6 x 150mm, 5µm) in an isocratic mode with mobile phase comprising of Acetonitrile: Pott. Dihydrogen Phosphate (pH 2.5 using OPA). The flow rate was 0.7 mL/ min and effluent was monitored at 254.0 nm. The stress conditions selected on the basis of literature review and the drug profile. For both estimations 99.81%for MET and 99.33% for PIOG mean % recovery was found with % RSD was NMT 2.0 which fully agrees by system suitability in good agreement with labeled claimed of formulation. All the parameters of system suitability were fully obeyed during force degradation profile generation.
subject: Review Articles
  topic: section
subject: MET
  topic: keywords
subject: PIOG
  topic: keywords
subject: RP-HPLC
  topic: keywords
subject: Stress,
  topic: keywords
subject: Department of Quality Assurance
  topic: disciplines
creator: Manoj S. Charde
rights: Copyright (c) 2015 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2022-01-30
publication date: 2022-01-30
starting page: 387
ending page: 394

Estimation of ibuprofen and famotidine by (RP-HPLC)
type: item
description: A force degradation profile by RP-HPLC method was developed for Ibuprofen (IBU) & Famotidine (FMT) in combine tablet dosage form using Cosmosil RP-C18 (4.6 x 250mm, 5µm) in an gradient mode with mobile phase comprising of Methanol: Water (pH 2.5 using OPA) The flow rate was 0.7 mL/ min and effluent was monitored at 240 nm. The stress conditions selected on the basis of literature review and drug profile. The analysis of the marketed formulation shows the % RSD of 0.061 and 0.35 for IBU & FMT which fully agrees with system suitability. All the system suitability parameters were fully obeyed during generation of force degradation profile
subject: Research Articles
  topic: section
subject: IBU
  topic: keywords
subject: FMT
  topic: keywords
subject: RP-HPLC
  topic: keywords
subject: Department of Quality Assurance
  topic: disciplines
creator: Manoj S. Charde
rights: Copyright (c) 2022 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2015-11-30
publication date: 2015-11-30
starting page: 380
ending page: 386

Management of vataj type of Shirshula with Goghrit Pratimarsha nasya- A case report
type: item
description: Shira is also known as Uttamanga in Ayurveda. It is the most vital part of our body. In Ayurveda, Shiro rogas are restricted to pain or discomfort seen around cranial vault and not the disorders of brain mostly. Headache is the most frequent and troublesome reason to seek medical help in our daily life. Tension type headache is the most common, primary, most neglected and difficult to treat occurring in about three-quarters of the general population. They can range from the occasional mild headaches to daily disabling headaches in some cases. Current allopathic approach is highly limited in treating the disease with just pain killers, which again have lot of side effects.Holistic Ayurveda approach practically is found to yield very good results in the patients of headache. Vataja Shiroroga can be an apt classical correlation of Tension-type headache. Atiuccha bhashana, Vegadharana, Ratrijagarana, Upavasa and Shoka are the major causes of Vataja shirashula. Classical books of Ayurveda advocate the use of Snehana, Swedana, Navana nasya, Snaihika dhumapana and local Vatahara kriya like Lepa and Parisheka as main mode of treatment. Nasya is a special therapy in all Shalakya disorders and Goghrita is considered as best Vatahara dravya. In this study, Goghrita pratimarsha nasya is done in a 29 year old patient having typical symptoms, to access the overall efficacy. After 1 month of therapy, significant improvement was seen in the symptoms. Mild recurrence was seen post follow-up period.
subject: Case Report
  topic: section
subject: Shiroroga
  topic: keywords
subject: Tension type headache
  topic: keywords
subject: Goghrita pratimarsha nasya
  topic: keywords
subject: Dravyaguna Vigyan
  topic: subjects
subject: Ayuveda
  topic: disciplines
creator: Niteen Ambatkar
creator: Namdeo Dorkhande
creator: Sunita Paradkar
rights: Copyright (c) 2021 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2021-10-25
publication date: 2021-10-25
starting page: e5688
ending page: e5688

HFMD- A Fuzzy Game Theory Model
type: item
description: In this project, we developed a fuzzy game theory model for Hand Foot Mouth disease (HFMD), a transmissible disease affecting many populations around the world. HFMD is fomented from the genus enteroviruses. Although there are several viruses, coxsackie virus enteroviruses 71 (EV71) and A16 [5] are most probable to produce this disease. Precise estimates of disease transmission rate are critical for epidemiological Game theory model. We considered the transmission co-efficient to be uncertain and described by a fuzzy number which is triangular and symmetric. We defuzzified the fuzzy number by a signed distance method and studied sensitivity analysis.
subject: Research Articles
  topic: section
subject: Game theory
  topic: keywords
subject: Nash equilibrium
  topic: keywords
subject: Triangular fuzzy number
  topic: keywords
subject: Mathematics
  topic: subjects
subject: Mathematics
  topic: disciplines
creator: H. Ross
creator: Ajanta Roy
creator: K. Smith
rights: Copyright (c) 2021 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2021-10-03
publication date: 2021-10-03
starting page: e5678
ending page: e5678

Systematizing Astrology for Constructive Approach
type: item
description: The research paper presents the hypothesis with the aim to contributes and uplift the standard of accuracy and precision in Astrology. It is an effort to systematize the analysis and prediction of horoscope by briefing the stages of feminine planets, reframing the aspects of Zodiac signs and establishing the subordinating relation between Lagan and Navmansh chart for systematic analysis.
subject: Research Articles
  topic: section
subject: hypothesis
  topic: keywords
subject: Astrology
  topic: keywords
subject: horoscope
  topic: keywords
subject: horoscope
  topic: disciplines
creator: Ashish Chauhan
rights: Copyright (c) 2021 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2021-10-06
publication date: 2021-10-06
starting page: e5676
ending page: e5676

Artificial Intelligence in Orthodontics: Prediction and Planning
type: item
description: Artificial intelligence (AI) with advancement of technology has experienced remarkable growth and development in the field of dentistry. AI is an excellent tool that performs several tasks from diagnosis, treatment planning, predicting the outcome and prognosis particularly in the field of orthodontics based on individual preferences and constructed algorithm models. The present review was carried out to discuss briefly on the role and impact of AI in the field of orthodontics. It was observed that most of the AI models are based on artificial neural networks (ANNs) and convolutional neural networks (CNNs) systems widely used for Cephalometric landmarks identification, image recognition, decision making system to assist treatment planning, prediction of need for extraction and/or orthognathic surgeries, evaluating the cervical vertebrae growth pattern and maturation, predicting the facial attractiveness and post-orthognathic surgery facial profile. Further research on application of AI should be carried out focusing on formulating and establishing cloud-based platforms, integrating large data to improve learning algorithms and construct advanced automated decision making model systems with high specificity, precision, reliability to predict exact outcomes within a short span of time and improve the quality of life.
subject: Review Articles
  topic: section
subject: Artificial Intelligence
  topic: keywords
subject: Automated diagnosis
  topic: keywords
subject: Customized treatment
  topic: keywords
subject: Clinical Decision Support Systems
  topic: keywords
subject: Neural Network
  topic: keywords
subject: Virtual systems
  topic: keywords
subject: SCIENCE AND TECHNOLOGY
  topic: disciplines
subject: DENTISTRY
  topic: disciplines
creator: Vinoth Kumar. R
creator: Abirami Vetriselvan
creator: Magdline A
creator: Rajakumar P
creator: M.K.Karthikeyan
rights: Copyright (c) 2021 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2021-10-03
publication date: 2021-10-03
starting page: e5672
ending page: e5672

Association between plasma homocysteine levels and coronary artery disease.
type: item
description: Objectives: Various studies have proposed that increased plasma homocysteine level causes both venous and arterial thrombosis contributing to myocardial Infarction, stroke, and pulmonary embolism, though the results are still debatable. In addition, the homocysteine levels show a genetic and ethnic predisposition. The present study thus aimed to evaluate the association between plasma homocysteine levels and coronary artery disease in Indian patients. Material and Methods: The present study was a hospital-based case-control study, conducted at a tertiary care hospital in North India. The study included 237 diagnosed cases of acute coronary syndrome (ACS) who were compared with 50 age and sex matched apparently healthy controls. Subjects of the two groups were compared for levels of plasma homocysteine, lipid profile and other conventional risk factors of coronary artery disease (CAD). Homocysteine levels were analysed by chemilumniscence immunoassay. Statistical analysis was performed using using SPSS v.21.0. Values were expressed as a mean ± standard deviation or as percentages. Student’s t test and Chi square test was used to evaluate statistical significance. Result: The mean homocysteine levels were found to be significantly higher (p<0.001) in patients of ACS as compared to the healthy controls. (14.34 ± 7.49 µmol/L and 11.34 ± 4.91µmol/L respectively). However, no association was found between homocysteine level and the conventional risk factors. Conclusion: The results suggest that high levels of homocysteine are associated with ACS and may be used for risk assessment of CAD. However, further studies with larger sample size would be required to validate the findings .
subject: Research Articles
  topic: section
subject: Coronary artery disease
  topic: keywords
subject: homocysteine
  topic: keywords
subject: risk factors
  topic: keywords
subject: Biochemistry
  topic: disciplines
subject: Cardiology
  topic: disciplines
creator: Siddharth Jindal
creator: Shivani Jaswal
creator: Sreenivas Reddy
creator: Seema Gupta
creator: Jasbinder Kaur
creator: Jeet Ram Kashyap
creator: Raghavendra Rao K
rights: Copyright (c) 2021 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2021-06-30
publication date: 2021-06-30
starting page: e5612
ending page: e5612

Genotoxicity effects of selected alcoholic polyherbal products using Allium cepa
type: item
description: Alcoholic herbal products have been used for years in folk medicine for its believed increase in sexual desire and pleasure. This study is due to the current upsurge in the use of polyherbal products and coupled with loose regulation on public access to these products, to evaluate their biochemical effect, noting also that many of the polyherbal products lack scientific evidence to support their medicinal claims. The objective is to investigate the potential genotoxicity of some commonly consumed polyherbal formulations (Action bitters, Black wood, Jedi-jedi, Agbara, Orijin bitters), using allium cepa. The method involves onion bulbs that were exposed to varied concentrations of herbal alcoholic productsfor microscopic analysis. Tap water has been used as a negative control. All the tested products have been observed to have genotoxic effects on cell division in Allium cepa, with the highest mitotic index as 59% (orijin bitters 25%) and the lowest being 23% (action bitters 75%). The results showed that all tested concentrations of alcoholic herbal products caused decreased mitotic index value and increased chromosomal aberration of Allium cepa root cells. From the findings, alcoholic polyherbal formulations may possess genotoxic effects.
subject: Research Articles
  topic: section
subject: Genotoxicity, meristematic cells, Allium cepa, alcoholic herbal products, cell division
  topic: keywords
subject: Biochemistry
  topic: disciplines
creator: Oluwaseyi Adetunji
creator: Ifeoluwa Hannah Oladipo
creator: Modupe Olusola Adetayo
creator: Gogonte Hezekiah Amah
creator: Adesola Moyosore Kuti
rights: Copyright (c) 2020 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2020-11-08
publication date: 2020-11-08
starting page: e5509
ending page: e5509

The Impact of Culture on Scientific Development
type: item
description: Scientific development in societies of the world is not even. Some societies are more developed scientifically than others. There are many possible reasons that could be offered to explain this. This work aimed at unravelling the role cultures play in the growth of science. The research uses creative philosophical analysis to arrive at the conclusion that most countries in spite of parading the same educational curriculum like their counterparts remain dwarfs scientifically. The difference in scientific development as discovered by these researchers is traceable to differences in culture. Though, culture greatly impact on science, it is also discovered that the level of scientific growth also determines how fast a culture would evolve. It implies that the two concepts have impacts on the development of each other.
subject: Review Articles
  topic: section
subject: Science
  topic: keywords
subject: culture
  topic: keywords
subject: interrelationship
  topic: keywords
subject: cause and effect
  topic: keywords
subject: funding
  topic: keywords
subject: Philosophy
  topic: disciplines
creator: Apologun Sylvester
creator: Bisong Peter Bisong
rights: Copyright (c) 2020 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2020-11-19
publication date: 2020-11-19
starting page: e5500
ending page: e5500

Astrology: A Scientific Purview
type: item
description: Astrology is a science based on facts and evidences that has significant accuracy and numerous applications. The paper is an attempt to explore the reasons of its unacceptability and ineffectiveness. There is need to pursue scientific astrological research to utilize its immense potential for human welfare, development, safety, bio-medical use and spiritual awakening.
subject: Review Articles
  topic: section
subject: Astrology
  topic: keywords
subject: Horoscope
  topic: keywords
subject: Mythology
  topic: keywords
subject: Astrological Sciences
  topic: subjects
subject: Astrological Sciences
  topic: disciplines
creator: Ashish Chauhan
rights: Copyright (c) 2020 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2020-07-30
publication date: 2020-07-30
starting page: e5455
ending page: e5455

Challenges of pandemic disease and mental health concern in Ethiopia: A systematic review of literature
type: item
description: Several studies have been carried out on the epidemiological nature, and economic, social, and psychological effects of pandemic diseases. However, little literature has been attempted to comprehensively indicate the psychological challenges of pandemic diseases and strategies utilized to overcome the challenges in the Ethiopian context. Thus, the objective of this comprehensive review of the literature was to assess and organize the literature on the challenges of pandemic diseases in general and COVID-19 in particular, develop guidelines and seek out alternative solutions that have implications for Ethiopia and beyond. The literature has been organized on the history, worldwide challenges of pandemics, Behavioural responses and coping mechanisms, and opportunities motivated by COVID-19. Some criteria were set to review the most relevant local and international studies that are rigorous in design, adequate sample size, relevant sample selection procedures, and those which have used instruments with high validity and reliability. The findings from the literature indicated that there is a high incidence of psychological difficulties (fear, stress, anxiety, and depression) associated with COVID-19 worldwide and in Ethiopia. The problem is attributed to economic, social, psychological, and health-related outcomes of COVID-19 that demand integrated prevention and intervention strategies.
subject: Review Articles
  topic: section
subject: Behavioural response
  topic: keywords
subject: COVID-19
  topic: keywords
subject: Ethiopia
  topic: keywords
subject: Mental health
  topic: keywords
subject: Pandemic disease
  topic: keywords
subject: Psychology
  topic: disciplines
subject: Educational psychology
  topic: disciplines
creator: Kumsa Donis Likisa
rights: Copyright (c)
date: 2020-06-30
publication date: 2020-06-30
starting page: e5438
ending page: e5438

Literature Review on the Bamboo as a Sustainable Material for Interiors with Its Potential and Market Assessment
type: item
description: Bamboo is one of the most fastest growing resources which provides wide opportunities as a cheap raw material to many sectors. Many industries are using bamboo as substitute raw material in different forms and while having a wide chain of demand and supply bamboo does not attain social status in many countries and still been considered as resource for poor class and named as
subject: Review Articles
  topic: section
subject: Bamboo, Sustainability , Bamboo Construction ,Life Cycle Assessment
  topic: keywords
subject: Bamboo Sustainability
  topic: subjects
subject: Architecture
  topic: disciplines
creator: Priyanka Shukla
rights: Copyright (c)
date: 2020-05-30
publication date: 2020-05-30
starting page: e5433
ending page: e5433

Is pre vaccination the reason for less morbidity and mortality for COVID-19 in India: an epidemiological study
type: item
description: As we all know the current rapid of the covid-19 in the most of the world has become a pandemic situation. Many research studies have been by various countries to develop a vaccines against the coronavirusSARS-CoV-2. Currently about six vaccine candidates have passed early testing and have entered the clinical trials across the globe, along with more than80 other candidates reported to be in preclinical stages. This state that many different approaches are being moved forward at the same time. However, the destinationis not yet completed and so no vaccines are currently licensed for any of the other coronaviruses affecting humans. If we go in the past few decades, various vaccines were given to geriatrics as well as paediatrics. So if we look the same in other countries the use of the vaccines is very less or instead some countries have no authentic grant to sell or use the vaccines. Here in this present study we are trying to propose that by the early use of the vaccines also reduced the number of reported COVID-19 cases in a country. So is the combination of these vaccines a reason for the reduced morbidity and mortality and can it be a boon to fight against the disaster of COVID-19 in future.
subject: Review Articles
  topic: section
subject: COVID-19
  topic: keywords
subject: Vaccines
  topic: keywords
subject: morbility
  topic: keywords
subject: mortality
  topic: keywords
subject: preclinical
  topic: keywords
subject: clinical testing
  topic: keywords
subject: Pharmacy
  topic: subjects
subject: Pharmacy
  topic: disciplines
creator: Ramesh D. Ingole
creator: Avinash B. Thalkari
creator: Pawan N. Karwa
rights: Copyright (c)
date: 2020-05-30
publication date: 2020-05-30
starting page: e5424
ending page: e5424

Histopathologic review of ovarian teratoma in Port Harcourt: A multicenter study
type: item
description: Background: Ovarian teratoma are the commonest germ cell tumours of the ovary commonly seen in the young but can occasionally be encountered in the elderly with an increased risk of malignant transformation. Method: This was an 8-year retrospective review of128 histologically confirmed cases of ovarian teratoma in the university of Port Harcourt teaching hospital and Braithwaite memorial specialist hospital both tertiary health facilities in Port Harcourt from 1st January 2009
subject: Research Articles
  topic: section
subject: Ovarian teratoma
  topic: keywords
subject: Histopathology
  topic: keywords
subject: Port Harcourt
  topic: keywords
subject: Anatomical Pathology
  topic: subjects
subject: Anatomical Pathology
  topic: disciplines
creator: Athanasius Boma Precious
creator: Bassey Goddy
rights: Copyright (c) 2020 International Journal of Advances in Scientific Research
date: 2020-02-29
publication date: 2020-02-29
starting page: e5363
ending page: e5363

Artificial neural networks for medical diagnosis: A review of recent trends
type: item
description: Artificial Intelligence systems (especially computer aided diagnosis and artificial neural network)are increasingly finding many uses in the medical diagnosis application in recent times. These methods are known to be adaptive learning algorithms that are capable of handling diverse types of medical data and integrate them into categorized outputs. In this study, we briefly review and discuss the concept, capabilities and applications of artificial neural network techniques to medical diagnosis, through consideration of some selected physical and mental diseases. The study focuses on scholarly researches within the years, 2010 to 2019.Findings show that no electronic online clinical database exist in Nigeria and the Sub-Saharan countries, most review researches in this area focused mainly on physical diseases without considering mental illnesses, the application of ANN in mental and comorbid disorders have not be thoroughly studies, ANN models and algorithms consider mainly homogeneous input data sources and not heterogeneous input data sources, and ANN models on multi-objective output systems are few as compared to single output ANN models.
subject: Review Articles
  topic: section
subject: Medical diagnosis
  topic: keywords
subject: Artificial intelligence
  topic: keywords
subject: Artificial neural networks
  topic: keywords
subject: Feed-forward back propagation
  topic: keywords
subject: Convolutional Neural Network
  topic: keywords
subject: diabetes
  topic: keywords
subject: cardiovascular
  topic: keywords
subject: cancer
  topic: keywords
subject: malaria and Mental Disorder
  topic: keywords
subject: Natural Sciences
  topic: disciplines
creator: Egba Anwaitu Fraser
creator: Okonkwo Obikwelu R.
rights: Copyright (c) 2020 International Journal of Advances in Scientific Research
date: 2020-01-31
publication date: 2020-01-31
starting page: e5353
ending page: e5353

Can technology save the environment?
type: item
description: The environment is fast degrading. Experts believe that in the nearest future, the environment will totally collapse, if the current rate of degradation continues. One of the main drivers of this degradation is believed to be technology. This has led to widespread perception of technology as a curse rather than a blessing to the environment and humanity. This work agrees that technology is one of the main causes of environmental problems but disagrees that technology is a curse. Technology in itself is value neutral; it is its usage that leads to bad or good consequences. It is the contention of these researchers, that technology when well driven could restore the health of the environment. Technology due to its wrong positioning in the past, has caused environmental problems. It could be repositioned to foster environmental health in the future. Technology therefore, has the potential, to restore and heal what it has wounded, when properly driven.
subject: Review Articles
  topic: section
subject: technology
  topic: keywords
subject: curse
  topic: keywords
subject: blessing
  topic: keywords
subject: environment
  topic: keywords
subject: degradation
  topic: keywords
subject: Educational Foundation
  topic: subjects
subject: Educational Foundation
  topic: disciplines
creator: Bisong Peter Bisong
creator: Apologun Sylvester
rights: Copyright (c) 2019 International Journal of Advances in Scientific Research
date: 2019-08-31
publication date: 2019-08-31
starting page: e5303
ending page: e5303

Anti-ulcer potential of the Ethanolic Extract of leavesof Solanum Violaceum in Wistar albino rats
type: item
description: The study evaluates the possible gastro protective of Ethanolic extract of leaves of Solanum violaceum [EESV] using two different gastric ulcer models. Gastric ulcers in Wistar albino rats were induced by Ethanol (1ml/200gm) and Indomethacin (30mg/kg) induced ulcer. Various parameters like Ulcer index, Acid volume, Total acidity, pH, Total protein, Glutathione, Catalase and Superoxide dismutase were evaluated. Omeprazole (20mg/kg) and Ranitidine (60mg/kg) was used as the standard drug. Solanum violaceum was administered at two dose levels, 250 mg/kg and 500 mg/kg body weight. Statistical analysis was done by ANOVA followed by Dunnet
subject: Research Articles
  topic: section
subject: Solanum violaceum
  topic: keywords
subject: Ethanol
  topic: keywords
subject: Indomethacin
  topic: keywords
subject: Omeprazole
  topic: keywords
subject: Ranitidine
  topic: keywords
subject: Pharmacology
  topic: subjects
subject: Pharmacology
  topic: disciplines
creator: Mamatha B. S.
creator: Palaksha M. N.
creator: Nandini K. N.
creator: Lekhana A. R.
rights: Copyright (c) 2020 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2020-03-30
publication date: 2020-03-30
starting page: e5396
ending page: e5396

Hepatitis C - Challenges and New Approaches in Vaccine Development
type: item
description: Hepatitis C continues to be the serious global health treat and hundreds of people die every year due to liver failure. Hepatitis C Virus, the virus that that won the battle with no vaccine till date to beat its survival. Despite 15 years of its discovery, no vaccine has come up eradicate the virus. The high genetic diversity and the resistant nature of the virus is halting the progress towards vaccine development however many promising new antiviral drugs are in clinical trials giving a hope that in the coming years a successful vaccine will be developed. Many approaches like inducing neutralising antibody, inducing T cell response, development of Direct Acting Antivirals and drugs targeting host proteins are being tried out for the development of a safe and effective vaccine for Hepatitis C, some of which are discussed in this review.
subject: Review Articles
  topic: section
subject: Hepatitis C
  topic: keywords
subject: Vaccine
  topic: keywords
subject: Antibodies
  topic: keywords
subject: T cell response
  topic: keywords
subject: Bioviz Technologies
  topic: disciplines
creator: Almas Shamaila
creator: Madhavi Chandra
creator: Khaja MN
rights: Copyright (c) 2019 International Journal of Advances in Scientific Research
date: 2019-07-31
publication date: 2019-07-31
starting page: e2566
ending page: e2566

Sensitivity of various methods (CMT, CE and Indicator Paper) of subclinical cattle mastitis diagnostic in some dairy cows breeding in east of Algeria
type: item
description: The aim of present work is to look for the prevalence of subclinical mastitis in dairy cows of different regions in eastern Algerian ; the prevalence of subclinical mastitis has called for three non-specific methods and by bacteriological analysis. On all teats are 416 ; the first non-specific test is Californiamastitis test (CMT) indicating polymorphonuclear witness infection of the udder. The second test indicates presence of ions (Na Cl) in milk and carries the appellation of the electrical conductivity of milk (EC) and the last test is the one that revealed the pH of milk while using papier pH containing pH indicator and changes color to green or blue if the udder is infected. It is the first component of the study; the second component is to get the bacteriological status of each udder and passing to the study of the sensitivity and specificity of non specifics tests . the present study gave values of mastitis prevalence between 6.7 to 64.7% of cows and 10 to 20% of udders tested by (CMT, pH papers and EC), with an infection rate of 9% of districts and 17% of cows. Bacteriological examination of positive areas showed the prevalence of the following pathogens : 6 species of Staph Saprophyticus= 15%, 6 species staph epidermidis=15%, 4 species staph cohnii=10%, 9 Staph +=22.5%, 2 Micrococcus. Spp=5%, 4 E.Coli=10%, 2 speciesof klebsielle =5%,2Proteus vulgaris=5%, 2Citrobacter freundeii=5%, 1 Streptococcus spp=2.5%, 1Streptococcus uberis=2.5%. et 5% others specie of bacterias. for specificity and sensitivity we have these values r : CMT = 71% and 77%;. For pH paper had values of 15% and 60% .in latter puts the EC with values of 13% and 67% respectively. So the CMT remains the most accessible and reliable tset
subject: Review Articles
  topic: section
subject: dairy cattle
  topic: keywords
subject: subclinical mastitis
  topic: keywords
subject: CMT
  topic: keywords
subject: Electrical Conductibility;
  topic: keywords
subject: ndicator papers
  topic: keywords
subject: bacteriological analysis
  topic: keywords
subject: Veterinary
  topic: subjects
subject: Production
  topic: disciplines
creator: Brahim Bouchoucha
creator: Omar Bouaziz
creator: Nourreddine Zeghilet
creator: Rachida Aimer
creator: Sana Hireche
creator: Sabrina Boussenna
rights: Copyright (c) 2018 International Journal of Advances in Scientific Research
date: 2018-04-01
publication date: 2018-04-01
starting page: 06
ending page: 12
doi: 10.7439/ijasr.v4i2.4615

Altitudinal Variation in Alkaloid Composition of Hyoscyamus niger: A study with reference to Kashmir region of Himalayas
type: item
description: The present study has been undertaken to understand the impact of altitude on the synthesis of alkaloids in Hyoscyamus niger found in Kashmir valley of Jand K state in India. Given its wide distributional range, the study aimed to quantify the alkaloids (hyoscyamine and scopolamine) in Hyoscyamus niger grown at various altitudes in Kashmir valley. The sampling of populations at varying altitudes allowed assessing the intraspecieac variation and ecological trends of accumulation of alkaloids in the plant. Furthermore the resource allocation in the parts of the plant has also been shown. The four different sites were Gulmarg, Pahalgam, Gurez and Qazigund in Kashmir valley. The study was able to identify the elite genotype and the best suited habitat (altitude) for commercial cultivation of the species with higher quantity of alkaloids.
subject: Research Articles
  topic: section
subject: Medical Plants
  topic: keywords
subject: Hyoscyamus niger
  topic: keywords
subject: Kashmir
  topic: keywords
subject: Alkaloids
  topic: keywords
subject: Altitudinal variation
  topic: keywords
subject: Chemistry
  topic: subjects
subject: Environmental Science
  topic: disciplines
creator: Sheema Zaffar
creator: Ieba Khan
creator: Asma Zaffar
creator: Azra N Kamili
rights: Copyright (c) 2018 International Journal of Advances in Scientific Research
date: 2018-05-14
publication date: 2018-05-14
starting page: 13
ending page: 17
doi: 10.7439/ijasr.v4i3.4728

Comparative studies of NiMnCo3O4 thin film electrodes for super capacitors applications
type: item
description: Present work is devoted to prepareternary NiMnCo3O4 electrodes by electrodeposition method on copper and porous copper substrate. The structural, morphological and electrochemical characterizations of the prepared samples studied and confirmed by using XRD, SEM, EDAX, FTIR and electrochemical measurements. Structural analysis confirms that NiMnCo3O4 film has face centred cubic with polycrystalline nature. Electrochemical measurements prove that NiMnCo3O4 electrode deposited on porous copper substrate has an improved supercapacitive behavior, compared with NiMnCo3O4 electrode deposited on copper substrate.A high specific capacity of 947 F/g at 10 mV/s was observed. Electrochemical performances were investigated atdifferent scan rate range. And it reveals the prepared electrode has excellent capacitance behaviour as well as reversibility. Moreover, stable cycle capability 90.2%inthe capacitance retention was achieved after 3000 cycles. This outstandingelectrochemical properties indicate that the obtained NiMnCo3O4 electrode materials are fairlyideal for supercapacitors.
subject: Research Articles
  topic: section
subject: Thin films
  topic: keywords
subject: Electrodeposition
  topic: keywords
subject: Nickel Manganese cobalt ternary oxide
  topic: keywords
subject: Super capacitor
  topic: keywords
subject: Science
  topic: subjects
subject: Physics
  topic: disciplines
creator: Kalyani M.
creator: R. N. Emerson
rights: Copyright (c) 2019 International Journal of Advances in Scientific Research
date: 2019-05-26
publication date: 2019-05-26
starting page: e5142
ending page: e5142

An updated review on pharmaceutical mini tablets: Formulation and it
type: item
description: The objective of controlled drug delivery systems is to reduce the frequency of the dosing and to increase the effectiveness of the drug. In oral controlled drug delivery system, multiple unit dosage forms (MUDF
subject: Review Articles
  topic: section
subject: Multiple unit dosage forms
  topic: keywords
subject: Single unit dosage forms
  topic: keywords
subject: Mini-tablets
  topic: keywords
subject: Pellets
  topic: keywords
subject: Pharmaceutics
  topic: subjects
subject: Pharmaceutics
  topic: disciplines
creator: Asif Nuruddin Shaikh
creator: Vishal Yadav
creator: Prakash Jadhav
rights: Copyright (c) 2019 International Journal of Advances in Scientific Research
date: 2019-03-31
publication date: 2019-03-31
starting page: e5109
ending page: e5109

Differentiated Ontologies
type: item
description: The specificity of the quantum metaphysics and a level of entourage and necessity placed over it indicates an essential characteristic of a given research paradigm and its exemplary structure. The interface of the meta-creativity and the cognitive consciousness provides an important impetus to the boon research and ideal innovative program, sometimes implicit. Thence it is a boon to analyse and examine the research contours of any problem from all aspects, imperatives and hypothetical stance.
subject: Short Communication
  topic: section
subject: Metaphysics
  topic: keywords
subject: Ontology
  topic: keywords
subject: Interontology
  topic: keywords
subject: Philosophy
  topic: keywords
subject: Social Science
  topic: subjects
subject: Social Sciences
  topic: disciplines
creator: Towseef Ahmad
rights: Copyright (c) 2018 International Journal of Advances in Scientific Research
date: 2018-12-31
publication date: 2018-12-31
starting page: 106
ending page: 107

Peptide Conjugated Lipid Nanoparticles and Cancer Drug Delivery
type: item
description: Peptide Conjugated Lipid Nanoparticles and their role on Cancer Drug Delivery are reviewed here. The benefits of nanotechnology and combination style of medicine delivery are still hindered without the active ligands needed for treatment efficacy. This work analyzes the role of peptide ligands in different forms of cancer treatments targeting cells and tissues.
subject: Review Articles
  topic: section
subject: Peptide-conjugated lipid nanoparticles,
  topic: keywords
subject: nanotechnology
  topic: keywords
subject: angiogenesis
  topic: keywords
subject: anti-angiogenesis
  topic: keywords
subject: lung cancer
  topic: keywords
subject: breast cancer
  topic: keywords
subject: Genetics
  topic: subjects
subject: Genetics
  topic: disciplines
creator: Wei Xiao
rights: Copyright (c) 2018 International Journal of Advances in Scientific Research
date: 2018-11-30
publication date: 2018-11-30
starting page: 95
ending page: 97

Study of the effect of intercropping on the physicochemical characteristics of castor bean, soybean, cowpea and common bean seeds after cultured in two agroecological zones of Cameroon
type: item
description: In order to promote the culture of castor bean, soybean, cowpea and d u bean in Cameroon while preserving food safety, the effect of the combination of the crop characteristics physicochemical seeds of this plant are studied in Laboratory after the cultivation of castor in combination with these three field grain legumes in Sudano-Guinean zone of Adamaoua and in the Eastern Bimodal Forest at Cameroon in 2015 and 2016. The physical characteristics such as length, width, thickness, seed mass and weight of one thousand seeds and chemical properties are the s of castor seeds (the moisture content, the content of castor bean, the mass density, the consumer acid, iodine, and saponification of esters) and Leguminous (the protein content, the sugar content and the ash content) are evaluated. The results show that the physico-chemical properties of castor seeds and legumes do not vary, regardless of the study zone, thus showing that these seeds can be grown in different zones without losing their characteristics. Castor bean contents of the grain is varied from 45.27
subject: Research Articles
  topic: section
subject: Castor bean
  topic: keywords
subject: Castor bean
  topic: keywords
subject: soybean
  topic: keywords
subject: soybean
  topic: keywords
subject: cropping system
  topic: keywords
subject: cropping system
  topic: keywords
subject: physico - chemical properties,
  topic: keywords
subject: physico - chemical properties,
  topic: keywords
subject: Sudano - Guinean zone
  topic: keywords
subject: Sudano - Guinean zone
  topic: keywords
subject: Sudano - Sahelian zone
  topic: keywords
subject: Sudano - Sahelian zone
  topic: keywords
subject: Cameroon
  topic: keywords
subject: Cameroon
  topic: keywords
subject: Cowpea
  topic: keywords
subject: Cowpea
  topic: keywords
subject: Sciences
  topic: subjects
subject: Sciences
  topic: subjects
subject: Biological Sciences
  topic: disciplines
subject: Biological Sciences
  topic: disciplines
creator: Derogoh Nway Amang Nhmie
creator: Megueni Clautilde
rights: Copyright (c) 2019 International Journal of Advances in Scientific Research https://creativecommons.org/licenses/by/4.0
date: 2019-01-30
publication date: 2019-01-30
starting page: e4863
ending page: e4863